The pain of gout has been with us for centuries, but a careful application of natural ingredients can easily help fight gout flare-ups and get sufferers back to their normal level of pain-free activity.  Our fast-acting and power packed formula includes: 

• Yucca Root Powder: Native Americans have used Yucca root extract for centuries to lower the symptoms associated with gout. Yucca contains saponins, which metabolize purines. Purines are substances in animal and plant foods that your body converts to uric acid. Gout is mainly caused by having too much uric acid in the body. (Reference: Arthritis Foundation. What Role Does Diet Play in Gout Management?)
  
  
• Tart Cherry Powder: Cherry is a nutritious fruit containing various antioxidants and other nutrients that can benefit patients with gout. A variety of different fruits are considered helpful in reducing uric acid levels, including cherries. The consumption of cherries has proven to be effective in lower urate levels in other research studies. (Reference: Collins, M.W.,  Saag, K.G., and Singh, J.A. (2019). Is there a role for cherries in the management of gout? Therapeutic Advances in Musculoskeletal Disease. vol. 11.)
  
  
• Alfalfa Powder: Alfalfa powder has been shown in studies to help neutralize and reduce the blood's uric acid levels. It also has natural antioxidant properties, making it an excellent alternative for people who suffer from gout. Alfalfa can boost the uric acid levels present in the urine, preventing it from overproducing, and thus pain can be less. (Reference: Kole, L., Giri, B., Manna, S.K., Pal, B., and Ghosh, S. (2011). Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation and blocking NFκB nuclear translocation. Eur J Pharmacol. 653(1-3):8-15.)
  
  
• Dandelion Leaf Powder: Dandelion leaf powder provides several health benefits. It has been shown to decrease uric acid levels and to support kidney health. It may increase urine production to allow more uric acid to be excreted from the body. (Reference: Corp, N., and Pendry, B. (2013). The role of Western herbal medicine in the treatment of gout. Journal of Herbal Medicine. 3(4):157–170.)
  
  
• Devil's Claw Powder: Devil's claw powder provides an anti-inflammatory effect because of the substances that make it taste bitter. Some studies suggest that the devil's claw may naturally support a moderate relief from pain. It is also a natural cleansing agent for toxic impurities. (Reference: Hostanska, K., Melzer, J., Rostock, M., Suter, A., and Saller, R. (2014). Alteration of anti-inflammatory activity of Harpagophytum procumbens (devil's claw) extract after external metabolic activation with S9 mix. J Pharm Pharmacol. 66(11):1606-14.)
  
  

• Garlic Powder: Garlic is a delicious addition to any dish. Garlic contains diallyl disulfide, an anti-inflammatory ingredient that regulates inflammation. Several essential compounds present in garlic may even help prevent cartilage damage. (Reference: Pareek, S., Dixit, M., Govil, S., and Jadhav, I. (2019). Garlic and Its Role in Arthritis Management. In book: Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases (pp.245-252) Publisher: Academic Press)

• Artichoke Leaf Powder: Artichoke is commonly used to support liver and heart health, but it also provides various health benefits to reduce inflammation. Artichokes may also support the digestive system to reduce bloating and promote consistency. They offer several antioxidants to help combat oxidative stress related to aging. (Reference: Rondanelli, M., Monteferrario, F., Perna, S., and Faliva, M. (2013). Health-promoting properties of artichoke in preventing cardiovascular disease by its lipidic and glycemic-reducing action. Università di Napoli, Secondo ateneo 80(1):17-26)
  
  
• Turmeric Extract: Turmeric is known for its anti-inflammatory properties and liver health properties mainly obtained from the active ingredient curcumin. It is used to flavor various dishes. Interestingly, several scientific studies indicate that it has potent anti-inflammatory and antioxidant properties. (Reference: Kiyani, M.M., Sohail, M.F., Shanhnaz, G., Rehman, H., Akhtar, M.F., Nawaz, I., Mahmood, T., Manzoor, M., and Bokhari, S.A.I. (2019). Evaluation of Turmeric Nanoparticles as Anti-Gout Agent: Modernization of a Traditional Drug. Medicina (Kaunas). 55(1): 10.)
  
  
• Milk Thistle Extract: Milk thistle, which contains silymarin, offers several health benefits for the liver. Since the liver is a vital organ that metabolizes uric acid, it is essential to have a healthy and efficient liver. Milk thistle is also a potent antioxidant with anti-inflammatory properties. (Reference: Vargas-Mendoza, N., Madrigal-Santillán, E., Morales-González, A., Esquivel-Soto, J., Esquivel-Chirino, C., García-Luna, M., González-Rubio, M.G.L., Gayosso-de-Lucio, J.A., and Morales-González, J.A. (2014). Hepatoprotective effect of silymarin. World J Hepatol. 27; 6(3): 144–149.)
  
  
• Celery Seed Extract: Celery has been used to support urinary or bladder health-related conditions. Also, celery may provide anti-inflammatory health benefits and other immune-enhancing and antioxidant properties that could help people with gout. (Reference: Li, S., Li. L., Yan, H., Jiang, X., Hu, W., Han, W., N., and Wang, D. (2019). Anti-gouty arthritis and anti-hyperuricemia properties of celery seed extracts in rodent models. Mol Med Rep. 20(5): 4623–4633.)
  
  
• Quercetin Dihydrate: Quercetin is a flavonoid, a type of antioxidant known to inhibit uric acid production. Quercetin is better absorbed when taken along the enzyme bromelain. Bromelain also reduces inflammation by decomposing the uric acid crystals, thus relieving you from the pain associated with gout. (Reference: Dhanasekar, C., Morin, R.M. (2016). A dietary bioflavonol suppresses monosodium urate crystalinduced inflammation in an animal model of acute gouty arthritis with reference to NLRP3 inflammasome, hypoxanthine phospho-ribosyl transferase, and inflammatory mediators. European Journal of Pharmacology. 786:116-127.)
  
  
• Mulberry Leaf Powder: Besides being highly nutritious and loaded with antioxidants, mulberries are considered tonics. They have traditionally been used to support kidney function and help with fatigue, anemia, and weakness. Mulberries have been shown in studies to regulate inflammation and other symptoms caused by gout.
  
  
• Burdock Root Powder: Burdock root contains a carbohydrate known as inulin. Inulin is also prebiotic that can support liver function. Several studies have shown that burdock root may enable the excess uric acid to pass through the urine and thus reduce inflammation.(Reference: Predes., F.S., Ruiz, A., Carvalho, J.E., Foglio, M.A., and Dolder, H. (2011). Antioxidative and in vitro antiproliferative activity of Arctium lappa root extracts. BMC Complement Altern Med. 11: 25.)
  
  
• Rutin: Rutin is commonly used to reduce the pain caused by arthritis. At the same time, rutin reduces oxidative stress caused by free radicals in people with several autoimmune conditions. Rutin offers potent anti-inflammatory and antioxidant properties that are essential to support these autoimmune conditions. (Reference: Chen, Y.S., Hu, Q.H., Zhang, X., Zhu, Q., and Kong, L.D. (2013). Beneficial Effect of Rutin on Oxonate-Induced Hyperuricemia and Renal Dysfunction in Mice. Pharmacology 2013; 92:75-83.)
  
  
• Boswellia Serrata Extract: Boswellia serrata grows in India's dry mountainous regions, Northern Africa, and the Middle East. Boswellia Serrata or frankincense has been used for centuries to provide pain relief from joint inflammation, arthritis, and gout. Boswellia serrata has several active ingredients like boswellic acids (acetyl-11-keto-β-boswellic acid) and other powerful anti-inflammatories compounds that may reduce inflammation. (Reference: Umar, S., Umar, K., Sarwar, A.H., Khan, A., Ahmad, N., Ahmad, S., Katiyar, C.K., Husain, S.A., Khan, H.A. (2014). Boswellia serrata extract attenuates inflammatory mediators and oxidative stress in collagen induced arthritis.; Phytomedicine. 15;21(6):847-56.)
  
  
• Bromelain: Bromelain is an enzyme found in the pineapples' juice and stems. Bromelain has shown to be an excellent anti-inflammatory agent. In several research studies, bromelain caused uric acid crystals to decompose, thus relieving the pain. (Reference: Wlaker, F.A., Bundy, R., Hicks, S.M., and Middleton, R.W. (2002). Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults. Phytomedicine 9: 681–686, 2002.)
  
  
• Folic Acid: Folic acid is commonly helpful to make healthy red blood cells, which carry oxygen around the body. If the body does not produce enough folic acid, it can make substantial red blood cells that do not work correctly. The side effect is that it causes folate deficiency, also known as anemia. Also, folic acid has been shown to regulate the production of uric acid. (Reference: Wu, X., Liu, J., Zhang, J., Liu, H., Yan, M., Liang, B., Xie, H., Zhang, S., Sun, B., and Zhou, H. (2016). Folic acid reverses uric acid crystal-induced surface OAT1 internalization by inhibiting RhoA activity in uric acid nephropathy. Mol Med Rep. 13(3): 2385–2392.)